3:30 pm Paul D. Coverdell Center for Biomedical and Health Sciences Room 175 Sponsored by: Biomedical and Health Sciences Institute Contact: Rebecca Ayer PR Coordinator 706-542-1016 Michelle Barton, professor of large animal medicine in the College of Veterinary Medicine, discusses her work on endotoxemia and heart function in horses and its crossover into human health.As a clinician scientist, UGA large animal professor Barton uses the information acquired from her background in the basic sciences in physiology, combines it with her training as a veterinary internal medicine specialist, and applies it to her patients at hand.  Those patients just happen to be horses. In her talk, "The Heart of the Matter: SIRS, MODS and the Colicky Horse," takes a One Health approach to one particular area of interest in her work, endotoxic shock.  Interestingly, endotoxemia is very common in horses with acute gastrointestinal disease ("colic") and thus horses are a fantastic model for endotoxemia or septic shock in people.  Barton's seminar will review what  endotoxemia, the systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS), and introduce a prospective clinical trial that focuses on heart function that is currently underway in horses admitted to the UGA Veterinary Teaching Hospital for acute surgical colic.   The One Health @ UGA Lectures Series aims to efforts at UGA and the Southeast focused on interdisciplinary teaching and learning, research, and outreach at the nexus of human, animal and ecological health.  It is supported by the BHSI Division of One Health.    BHSI Division of One Health